Within a current review, we noted the identification as well as characterization of a new atypical opioid receptor with exceptional detrimental regulatory Houses towards opioid peptides.1 Our results showed that ACKR3/CXCR7, hitherto called an atypical scavenger receptor for chemokines CXCL12 and CXCL11, is likewise a broad-spectrum scavenger for o